CASP Randomized Controlled Trial Checklist
CASP Randomized Controlled Trial Checklist
General Items
- Ensure transparency and reproducibility
- Follow CONSORT guidelines for reporting
- Engage stakeholders in the trial design
Before the Trial
- Specify the research question
- Identify the target population
- Define inclusion and exclusion criteria
- Determine sample size
- Select randomization method
- Obtain ethical approval
- Register the trial
Conducting the Trial
- Ensure participant consent is obtained
- Implement randomization process
- Monitor adherence to intervention protocol
- Collect baseline data
- Ensure blinding where applicable
Data Analysis
- Specify analysis plan in advance
- Conduct intention-to-treat analysis
- Handle missing data appropriately
- Compare baseline characteristics of groups
Reporting Results
- Provide flow diagram of participant flow
- Report demographic and clinical characteristics
- Present outcome measures clearly
- Discuss findings in context of previous research
- Acknowledge limitations of the study
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